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Additional criteria for sample release

The request must relate to a hypothesis-driven study
The study must be deemed by the Executive of CHILD to be fundamentally important to the core objectives of the CHILD study
A strong rationale for the need for a longitudinal study design must be evident
There must be clarity on the precise samples needed and the volumes required
Evidence must be presented that the assays to be employed, and the laboratory to conduct the assays, have high quality control and quality assurance
The assays selected must be state-of-the-art, require minimal sample volumes and provide maximum data output; e.g., contrast single parameter analyses versus multiplex assays
Information must be provided on funding mechanisms for sample analyses and the study completion
Evidence must be provided that ethics approval is available
Rationale must be provided as to why the requested samples are required at the current time, rather than after completion of the Study’s 5-year follow-up, with the potential at that time for a more efficient study design; e.g., nested case-controls, etc.

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