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2024

Shedding light on how mom’s genes influence health-boosting sugars in human milk

Amirthagowri Ambalavanan, Kozeta Miliku, Stuart E. Turvey, Piushkumar J. Mandhane, Elinor Simons, Theo J. Moraes, Sonia S. Anand, Guillaume Paré, Malcolm R. Sears, Padmaja Subbarao, Meghan B. Azad, Qingling Duan HMOs, human milk oligosaccharides, breast milk, human milk, breastfeeding, respiratory health, GWAS, genome, genetics, asthma, wheeze Hamilton
2024

Breastmilk microbes are shaped by mom’s genes and influence her child’s asthma and allergy risk, study finds

Zhi Yi Fang, Sara A. Stickley, Amirthagowri Ambalavanan, Yang Zhang, Amanda M. Zacharias, Kelsey Fehr, Shirin Moossavi, Charisse Petersen, Kozeta Miliku, Piushkumar J. Mandhane, Elinor Simons, Theo J. Moraes, Malcolm R. Sears, Michael G. Surette, Padmaja Breast milk, human milk, breastfeeding, microbiome, microbes, bacteria, asthma, allergy, allergic sensitization, genome, genomics, GWAS, Hamilton
2024

New study reveals how breastfeeding shapes a child’s microbiome and lung health

Kelsey Fehr, Myrtha E. Reyna, Charisse Petersen, Darlene L.Y. Dai, Ruixue Dai, Vanessa Breton, Elinor Simons, Lars Bode, Jean S. Marshall, Theo J. Moraes, Piush J. Mandhane, Stuart E. Turvey, Padmaja Subbarao, Michael G. Surette, Meghan B. Azad breastfeeding, human milk, microbiome, microbes, bacteria, lung health, respiratory health, asthma Hamilton
2023

CHILD provides first Canadian data on gas stove use & asthma risk

Padmaja Subbarao, Jeffrey R. Brook, Piush Mandhane, Stuart Turvey, Theo J. Moraes, Elinor Simons, Marc-Antoine Bédard, Myrtha E. Reyna asthma risk, gas stoves Hamilton
2023

CHILD researchers discover common origin behind major childhood allergies

Stuart Turvey, Charisse Petersen, Courtney Hoskinson microbiome, bacteria, allergies, eczema, allergic rhinitis, food allergy, antibiotics Vancouver
2022

New tool allows primary caregivers to predict asthma risk early

Padmaja Subarao, Malcolm Sears asthma risk, wheeze, cough, lung function Hamilton
2021

A mother’s prenatal egg intake may influence her child’s food allergy risk

Elinor Simons, Keely Loewen prenatal maternal egg consumption, pregnancy, food allergy risk, sensitization Winnipeg
2021

Phthalate exposure in house dust during baby’s first year associated with later asthma risk

Jeffrey Brook, Garthika Navaranjan, Chris Carlsten phthalates, house dust, childhood asthma risk, household chemicals, wheeze, di-2-ethylhexyl phthalate (DEHP), urine Hamilton
2021

A newborn’s dirty diaper may help predict allergy risk

B. Brett Finlay, Charisse Petersen, Stuart Turvey meconium, infant gut microbiome, allergy risk, immune development, sensitization Hamilton
2021

Makeup of fungi in baby’s gut may influence allergies at age 5

Rozlyn Boutin, B. Brett Finlay, Stuart Turvey infant gut microbiome, fungi, allergies, allergic sensitization, inhaled allergens, house dust, mites, pollen, animal dander, mould, mycobiota, antibiotic use, siblings, breastfeeding, fungal communities Hamilton
2021

CHILD Cohort Study releases new COVID-19 Rapid Results data

Meghan Azad, Padmaja Subbarao COVID-19, data, pandemic, infection Hamilton
2020

“Triple exposure:” Mom eating peanut, breastfeeding and introducing peanut early could help protect against peanut allergy in children

Meghan Azad, Malcolm Sears peanut, breastfeeding, early introduction, food allergy risk, allergic sensitization, maternal consumption, triple exposure, allergenic, milk, peanut, diet Winnipeg
2020

Birth factors influence infant gut microbiome and risk of childhood obesity and allergies

Anita Kozyrskyj, Khanh Vu Gastroenterology, University of Alberta, cesarean delivery, gut microbiome, prolonged labour, pathways, Enterobacteriaceae, Bacteroidaceae, Clostridioides difficile, C. difficile, first pregnancy, stool, skin prick test, allergic sensitization, metabolite Edmonton
2020

Alberta funds COVID-19 antibody testing among Edmonton children in CHILD Cohort Study

Piush Mandhane, Padmaja Subbarao COVID-19 antibody prevalence, Government of Alberta, University of Alberta, Serologic tests, blood Edmonton
2020

Living close to natural green space benefits gut bacteria of urban, formula-fed infants, study shows

Anita Kozyrskyj Environment International, SyMBIOTA, University of Alberta, natural green space, infant gut bacteria, microbiome, formula feeding, breastfeeding, stool, postal codes, microbial diversity, pets, dog, fur, household dust, delivery mode, caesarean section, Edmonton
2020

CHILD Cohort Study awarded $1.7M to study impacts of COVID-19 on Canadian families

Meghan Azad, Padmaja Subbarao, Piush Mandhane, Theo Moraes, Stuart Turvey CIHR, Research Manitoba, COVID-19, pandemic, risk factors, mental health, wellbeing, policies, biological samples, coronavirus infection, psychosocial data, antibody testing, Public Health Agency of Canada Winnipeg
2020

Exposure to cleaning products in first 3 months of life can increase risk of childhood asthma

Tim Takaro, Jaclyn Parks Canadian Medical Association Journal (CMAJ), Simon Fraser University, household cleaning products, asthma risk, childhood wheeze, atopy, respiratory problems, sex, male, female, detergents, disinfectants, air fresheners, deodorizers, dusting sprays, antim Vancouver
2020

CHILD Cohort Study researchers awarded $2M to study microbial causes of asthma

Padmaja Subbarao, Meghan Azad, Qingling Duan, Jeremy Hirota, Anita Kozyrskyj, Wendy Lou, Kelly McNagny, Michael Surette, Stuart Turvey Canadian Microbiome Initiative 2 (CMI2), award, asthma, microbiome, genetics, sex, early-life exposures, breastmilk, antibiotics, mice, gut bacteria Winnipeg
2020

Influence of vitamin D supplementation on a baby’s gut microbiome

Anita Kozyrskyj, Kelsea Drall Gut Microbes, vitamin D supplementation, gut microbiome, bacteria Megamonas, stool, asthma, respiratory viral infections, Clostridioides difficile, C. difficile, breastfeeding, respiratory syncytial virus (RSV), COVID-19 Edmonton
2020

Mom and baby share “good bacteria” through breastmilk

Meghan Azad, Stuart Turvey, B. Brett Finlay, Kelsey Fehr, Shirin Moossavi, Rozlyn Boutin, Hind Sbihi Cell Host & Microbe, University of Manitoba, University of British Columbia (UBC), bacteria, breastmilk, direct breastfeeding, infant gut microbiome, Streptococcus, Veillonella, stool, pumped milk, bottle-feeding, exclusivity, duration, milk bacteria, mil Winnipeg
2020

Falling childhood asthma rates linked to declining use of unnecessary antibiotics

Stuart Turvey, B. Brett Finlay, David Patrick, Hind Sbihi Lancet Respiratory Medicine, BC Children’s Hospital, BC Centre for Disease Control (BCCDC), University of British Columbia (UBC), unnecessary antibiotics, childhood asthma, gut bacteria, microbiome, antibiotic resistance, drug reactions, Vancouver
2020

Mom’s depression in late pregnancy may impact her baby’s immune system

Anita Kozyrskyj, Liane Kang, Clinical Experimental Allergy, University of Alberta, mother, maternal psychological wellbeing during pregnancy, immune health, newborn, depression, late pregnancy, antibody, secretory immunoglobulin A (sIgA), distress, allergy risk, gut immunity, microbi Edmonton
2019

Even infants at low risk of peanut allergy should eat peanut early

Elinor Simons Journal of Allergy and Clinical Immunology: In Practice, peanut allergy, early introduction, food allergy, timing, low-risk, delayed introduction of potentially allergenic foods Winnipeg
2019

Fats in breastmilk are unique to each mother

Meghan Azad, Kozeta Miliku, Catherine Field American Journal of Clinical Nutrition, breastmilk, nutrients, longchain polyunsaturated fatty acids, breast milk fats, mothers, diet, fish, omega-3, omega-6, body mass index (BMI), pregnancy, DHA (docosahexaenoic acid), infant brain development Winnipeg
2019

Screen time associated with behavioural problems in preschoolers

Piush Mandhane, Sukhpreet Tamana PLOS One, University of Alberta, screen time, screen-time, behavioural problems, inattention, attention deficit hyperactivity disorder (ADHD), guidelines, Child Behavior Checklist (CBCL), sleep, organized sports, physical activity, Edmonton
2019

Breastmilk microbiome linked to method of feeding

Meghan Azad, Shirin Moossavi breastmilk, microbiome, microbiota, bacteria, gut, mouth, breastfeeding, direct, indirect, pumped, oral, formula Winnipeg
2019

Air pollution exposure in early pregnancy linked to infants’ risk of developing allergies

Stuart Turvey, Hind Sbihi, Michael Kobor Journal of Allergy and Clinical Immunology, mother, exposure to traffic-related air pollution (TRAP), pregnancy, allergic sensitization, in utero, asthma, allergies, skin prick test, food allergy, inhaled allergens, Epigenetic gestational age (eGA), ges Hamilton
2019

Infant sleep duration associated with mother’s level of education, prenatal depression and method of delivery

Piush Mandhane, Anita Kozyrskyj, Brittany Matenchuk Sleep Medicine, University of Alberta, level of education, prenatal depression, method of delivery, infant sleep duration, maternal distress, emergency cesarean section, vaginal delivery, birth mode Edmonton
2018

“Every feed counts”: Breastfeeding may protect against obesity in early life

Meghan Azad breastfeeding, obesity, exclusive, dose dependent, Pediatrics, infant weight gain, cardiovascular health, expressed, bottle, pumped, formula, direct, indirect, freezing, thawing, heating, overweight Winnipeg
2018

Household cleaners may cause obesity in young children

Anita Kozyrskyj, Mon Tun University of Alberta, CIHR, Canadian Medical Association Journal (CMAJ), SyMBIOTA, household disinfectants, cleaners, obesity, risk, Lachnospiraceae, infant gut microbiome, body mass index (BMI), overweight, detergents, eco-friendly, multi-surface, aeros Edmonton
2018

Maternal depression higher among certain ethnic minorities

Padmaja Subbarao, Christoffer Dharma mothers, black, first nations, ethnic minorities, maternal depression, stress, pregnant, psychosocial distress, Canadian Journal of Psychiatry, ethnicity, depressive symptoms Hamilton
2018

Lung Clearance Index a sensitive marker for infants at risk for asthma

Padmaja Subbarao, Zihang Lu Lung Clearance Index (LCI), asthma, risk, airway disease, airways, Thorax, recurrent wheezing, wheeze, Multiple Breath Washout (MBW), lung function in infants, lung disease Hamilton
2018

Infants who sleep less may have lower cognitive and language skills by age two

Piush Mandhane, Lisa Smithson sleep disruption, cognitive, language skills, snore, sleep-disordered breathing (SDB), apnea, nighttime, nose and ear infections, hearing, speech, viral infections, daycare attendance, skin-prick test, allergic sensitization, acid reflux, smoke, dogs, div Edmonton
2018

Breastmilk sugars may help prevent food allergies

Meghan Azad, Kozeta Miliku, Lars Bode breastmilk, sugars, food allergies, Allergy, sensitization, human milk oligosaccharides (HMOs), skin prick tests, infant gut microbiome, bacteria, bioactive components Winnipeg
2018

Infant feeding practices influence a baby’s gut bacteria and risk of becoming overweight

Meghan Azad, Anita Kozyrskyj, James Scott, Jessica Forbes infant feeding, gut bacteria, gut microbiome, overweight, exclusive breastfeeding, partial, formula, JAMA Pediatrics, Lachnospiracae, DNA sequences, SyMBIOTA, complementary foods, hospital stay Winnipeg
2018

Exclusive breastfeeding in hospital associated with longer breastfeeding duration

Meghan Azad, Lorena Vehling, Maria Mackay, Marusia Kachkowski exclusive breastfeeding in hospital, duration, formula supplementation, education level Winnipeg
2018

C-sections and gut bacteria increase risk of childhood obesity

Anita Kozyrskyj, James Scott, David Guttman, Hein Min Tun C-section, gut bacteria, childhood obesity, overweight, vaginal birth, cesarean section, gut microbiome, JAMA Pediatrics, stool, sequential mediation, Lachnospiracae Edmonton
2018

CHILD Study researchers awarded $9.1M toward search for asthma clues in dirty diapers

Stuart Turvey, Padmaja Subbarao, Michael Kobor, B. Brett Finlay, Allan Becker, Meghan Azad, Fiona Brinkman, Timothy Caulfield,Piush Mandhane,Sara Mostafavi, Anna Goldenberg, Theo Moraes, Wendy Lou, Malcolm Sears Genome Canada, award, childhood asthma, gut microbiome, genomic, stool, microbes Hamilton
2017

Study finds delayed food introduction increases risk of sensitization

Malcolm Sears, Maxwell Tran Pediatric Allergy and Immunology, potentially allergenic foods, timing, delay, early introduction, cow’s milk products, egg, peanut, sensitization, wheeze, asthma, eczema, allergic rhinitis, CIHR Hamilton
2017

Can breastfeeding help protect babies from wheezing?

Meghan Azad European Respiratory Journal, wheezing, wheeze, exclusive breastfeeding, breastmilk, asthma, complementary foods, formula, smoking, education Winnipeg
2017

Pet exposure during early life affects infant gut microbiota

Anita Kozyrskyj, James Scott, David Guttman, Hein Min Tun furry pets, infant gut microbiota, microbiome, allergic disease, asthma, childhood obesity, bacteria, Group B Streptococcus, DNA sequencing, stool, Microbiome, Nature Outlook Edmonton
2017

Asthma in infant boys may eventually be preventable

Anita Kozyrskyj University of Alberta, asthma, microbes, gut microbiome, Caucasian, boys, Lactobacillus, sex, girls, Bacteroidaceae, puberty, gender switch, European Respiratory Journal Edmonton
2017

Study finds asthma and food allergies predictable at age one

Malcolm Sears, Maxwell Tran, Judah Denburg asthma, food allergies, eczema, atopic dermatitis (AD), The Journal of Allergy and Clinical Immunology, atopic march, allergic sensitization, allergic rhinitis, early introduction, food allergy Hamilton
2017

Stress in pregnancy may affect a baby’s immune system

Anita Kozyrskyj, Liane Kang Brain, Behavior and Immunity, maternal distress, pregnancy, immune system, pre- and postnatal depression, antibody, stress-microbiome-immunity pathway, allergic disease, gut microbiome, allergies, secretory immunoglobulin A (sIgA), breastmilk, exclusive b Edmonton
2017

Asthma risk lower with direct breastfeeding

Meghan Azad, Annika Klopp asthma risk, direct breastfeeding, formula, expressed breastmilk, The Journal of Pediatrics, freezing, thawing, heating, pumping, suckling, lungs Winnipeg
2017

Breastmilk hormones may help prevent obesity in infants

Meghan Azad, Deborah Chan breastmilk hormones, obesity, human milk, International Journal of Obesity, adiponectin, leptin, insulin, weight-for-length (WFL), body mass index (BMI), ethnicity, age, breastfeeding exclusivity, overweight Winnipeg
2017

CHILD Study researchers uncover immune status “shift” during healthy pregnancy

Kent HayGlass immune status shift, healthy pregnancy, anti-inflammatory Winnipeg
2017

CHILD Study data to support new research into child lung health

Teresa To, Padmaja Subbarao, Wendy Lou The Hospital for Sick Children (SickKids), award, lung disease, CIHR, air quality, asthma Toronto
2017

CHILD Study team to study how prenatal artificial sweetener intake affects infant weight

Meghan Azad, Marie-Claire Arrieta University of Manitoba, University of Calgary, CIHR, artificial sweeteners, pregnancy, infant weight gain, overweight, microbiome, metabolism, obesity, air quality, lung health, maternal diet Winnipeg
2016

UAlberta study shows infants do better on developmental tests when their mothers consume more fruit during pregnancy

Piush Mandhane, Francois Bolduc University of Alberta, EBioMedicine, prenatal fruit consumption, developmental testing, cognitive development, maternal diet, pregnancy, IQ scale, fruit flies, brain function Edmonton
2016

Consumption of artificially sweetened beverages in pregnancy influences infant BMI

Meghan Azad JAMA Pediatrics, body mass index (BMI), artificial sweeteners, in utero, maternal diet, pregnancy, overweight, obesity Winnipeg
2016

CHILD Study researchers to study environment’s impact on chronic diseases

Malcolm Sears award, CIHR, lung health, respiratory diseases, asthma, obesity, cardiometabolic disease Hamilton
2015

Antibiotic use during birth affects infant gut microbiota

Anita Kozyrskyj, James Scott, David Guttman, Meghan Azad antibiotics, birth, infant gut microbiota, microbiome, labour, delivery, breastfeeding, Bacteroidaceae, Clostridiales, CIHR Edmonton
2015

Four gut bacteria decrease asthma risk in first 100 days of life

Brett Finlay, Stuart Turvey gut bacteria, asthma risk, microbiome, microbiota, Science Translational Medicine, FLVR, Faecalibacterium, Lachnospira, Veillonella, Rothia, CIHR, hygiene hypothesis, mice Vancouver
2015

Asthma Society of Canada announces “Clearing the Air” award for leadership in health research

Malcolm Sears award, asthma research, leadership, prize Hamiton
2015

Environmental-exposures study tracks more than 3,200 Canadian babies

Tim Takaro, Malcolm Sears indoor and outdoor environmental exposures, Journal of Exposure Science and Environmental Epidemiology, homes, dust, mould, furry pets, chemicals, cleaning products, cooking emissions, second-hand smoke, traffic-related air pollution Vancouver
2015

Exposure to air pollution in the first year of life increases risk for allergies

Michael Brauer, Hind Sbihi Environmental Health Perspectives, outdoor air pollution, allergies, traffic-related air pollution, allergic sensitization, furry pets, attached garage, daycare, siblings Vancouver
2015

Infant gut bacteria and food sensitization: associations in the first year of life

Anita Kozyrskyj, James Scott, David Guttman, Meghan Azad infant b=gut bacteria, microbiome, microbiota, food sensitization, allergy, asthma, Clinical & Experimental Allergy, Enterobacteriaceae, Bacteroidaceae, skin prick test Edmonton
2013

AllerGen researchers find infant gut bacteria is influenced by delivery and feeding methods and may have long-term health effects

Meghan Azad, Anita Kozyrskyj infant gut bacteria, microbiome, microbiota, mode of delivery, birth, vaginal, cesarean section, exclusive, partial, breastfeeding, formula, asthma, allergies, cancer, type II diabetes, infant diet Edmonton