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Year | Title | Investigators | Details | City |
---|---|---|---|---|
2024 |
Shedding light on how mom’s genes influence health-boosting sugars in human milk |
Amirthagowri Ambalavanan, Kozeta Miliku, Stuart E. Turvey, Piushkumar J. Mandhane, Elinor Simons, Theo J. Moraes, Sonia S. Anand, Guillaume Paré, Malcolm R. Sears, Padmaja Subbarao, Meghan B. Azad, Qingling Duan | HMOs, human milk oligosaccharides, breast milk, human milk, breastfeeding, respiratory health, GWAS, genome, genetics, asthma, wheeze | Hamilton |
2024 | Zhi Yi Fang, Sara A. Stickley, Amirthagowri Ambalavanan, Yang Zhang, Amanda M. Zacharias, Kelsey Fehr, Shirin Moossavi, Charisse Petersen, Kozeta Miliku, Piushkumar J. Mandhane, Elinor Simons, Theo J. Moraes, Malcolm R. Sears, Michael G. Surette, Padmaja | Breast milk, human milk, breastfeeding, microbiome, microbes, bacteria, asthma, allergy, allergic sensitization, genome, genomics, GWAS, | Hamilton | |
2024 |
New study reveals how breastfeeding shapes a child’s microbiome and lung health |
Kelsey Fehr, Myrtha E. Reyna, Charisse Petersen, Darlene L.Y. Dai, Ruixue Dai, Vanessa Breton, Elinor Simons, Lars Bode, Jean S. Marshall, Theo J. Moraes, Piush J. Mandhane, Stuart E. Turvey, Padmaja Subbarao, Michael G. Surette, Meghan B. Azad | breastfeeding, human milk, microbiome, microbes, bacteria, lung health, respiratory health, asthma | Hamilton |
2023 |
CHILD provides first Canadian data on gas stove use & asthma risk |
Padmaja Subbarao, Jeffrey R. Brook, Piush Mandhane, Stuart Turvey, Theo J. Moraes, Elinor Simons, Marc-Antoine Bédard, Myrtha E. Reyna | asthma risk, gas stoves | Hamilton |
2023 |
CHILD researchers discover common origin behind major childhood allergies |
Stuart Turvey, Charisse Petersen, Courtney Hoskinson | microbiome, bacteria, allergies, eczema, allergic rhinitis, food allergy, antibiotics | Vancouver |
2022 |
New tool allows primary caregivers to predict asthma risk early |
Padmaja Subarao, Malcolm Sears | asthma risk, wheeze, cough, lung function | Hamilton |
2021 |
A mother’s prenatal egg intake may influence her child’s food allergy risk |
Elinor Simons, Keely Loewen | prenatal maternal egg consumption, pregnancy, food allergy risk, sensitization | Winnipeg |
2021 |
Phthalate exposure in house dust during baby’s first year associated with later asthma risk |
Jeffrey Brook, Garthika Navaranjan, Chris Carlsten | phthalates, house dust, childhood asthma risk, household chemicals, wheeze, di-2-ethylhexyl phthalate (DEHP), urine | Hamilton |
2021 | B. Brett Finlay, Charisse Petersen, Stuart Turvey | meconium, infant gut microbiome, allergy risk, immune development, sensitization | Hamilton | |
2021 |
Makeup of fungi in baby’s gut may influence allergies at age 5 |
Rozlyn Boutin, B. Brett Finlay, Stuart Turvey | infant gut microbiome, fungi, allergies, allergic sensitization, inhaled allergens, house dust, mites, pollen, animal dander, mould, mycobiota, antibiotic use, siblings, breastfeeding, fungal communities | Hamilton |
2021 | Meghan Azad, Padmaja Subbarao | COVID-19, data, pandemic, infection | Hamilton | |
2020 | Meghan Azad, Malcolm Sears | peanut, breastfeeding, early introduction, food allergy risk, allergic sensitization, maternal consumption, triple exposure, allergenic, milk, peanut, diet | Winnipeg | |
2020 |
Birth factors influence infant gut microbiome and risk of childhood obesity and allergies |
Anita Kozyrskyj, Khanh Vu | Gastroenterology, University of Alberta, cesarean delivery, gut microbiome, prolonged labour, pathways, Enterobacteriaceae, Bacteroidaceae, Clostridioides difficile, C. difficile, first pregnancy, stool, skin prick test, allergic sensitization, metabolite | Edmonton |
2020 |
Alberta funds COVID-19 antibody testing among Edmonton children in CHILD Cohort Study |
Piush Mandhane, Padmaja Subbarao | COVID-19 antibody prevalence, Government of Alberta, University of Alberta, Serologic tests, blood | Edmonton |
2020 |
Living close to natural green space benefits gut bacteria of urban, formula-fed infants, study shows |
Anita Kozyrskyj | Environment International, SyMBIOTA, University of Alberta, natural green space, infant gut bacteria, microbiome, formula feeding, breastfeeding, stool, postal codes, microbial diversity, pets, dog, fur, household dust, delivery mode, caesarean section, | Edmonton |
2020 |
CHILD Cohort Study awarded $1.7M to study impacts of COVID-19 on Canadian families |
Meghan Azad, Padmaja Subbarao, Piush Mandhane, Theo Moraes, Stuart Turvey | CIHR, Research Manitoba, COVID-19, pandemic, risk factors, mental health, wellbeing, policies, biological samples, coronavirus infection, psychosocial data, antibody testing, Public Health Agency of Canada | Winnipeg |
2020 |
Exposure to cleaning products in first 3 months of life can increase risk of childhood asthma |
Tim Takaro, Jaclyn Parks | Canadian Medical Association Journal (CMAJ), Simon Fraser University, household cleaning products, asthma risk, childhood wheeze, atopy, respiratory problems, sex, male, female, detergents, disinfectants, air fresheners, deodorizers, dusting sprays, antim | Vancouver |
2020 |
CHILD Cohort Study researchers awarded $2M to study microbial causes of asthma |
Padmaja Subbarao, Meghan Azad, Qingling Duan, Jeremy Hirota, Anita Kozyrskyj, Wendy Lou, Kelly McNagny, Michael Surette, Stuart Turvey | Canadian Microbiome Initiative 2 (CMI2), award, asthma, microbiome, genetics, sex, early-life exposures, breastmilk, antibiotics, mice, gut bacteria | Winnipeg |
2020 |
Influence of vitamin D supplementation on a baby’s gut microbiome |
Anita Kozyrskyj, Kelsea Drall | Gut Microbes, vitamin D supplementation, gut microbiome, bacteria Megamonas, stool, asthma, respiratory viral infections, Clostridioides difficile, C. difficile, breastfeeding, respiratory syncytial virus (RSV), COVID-19 | Edmonton |
2020 | Meghan Azad, Stuart Turvey, B. Brett Finlay, Kelsey Fehr, Shirin Moossavi, Rozlyn Boutin, Hind Sbihi | Cell Host & Microbe, University of Manitoba, University of British Columbia (UBC), bacteria, breastmilk, direct breastfeeding, infant gut microbiome, Streptococcus, Veillonella, stool, pumped milk, bottle-feeding, exclusivity, duration, milk bacteria, mil | Winnipeg | |
2020 |
Falling childhood asthma rates linked to declining use of unnecessary antibiotics |
Stuart Turvey, B. Brett Finlay, David Patrick, Hind Sbihi | Lancet Respiratory Medicine, BC Children’s Hospital, BC Centre for Disease Control (BCCDC), University of British Columbia (UBC), unnecessary antibiotics, childhood asthma, gut bacteria, microbiome, antibiotic resistance, drug reactions, | Vancouver |
2020 |
Mom’s depression in late pregnancy may impact her baby’s immune system |
Anita Kozyrskyj, Liane Kang, | Clinical Experimental Allergy, University of Alberta, mother, maternal psychological wellbeing during pregnancy, immune health, newborn, depression, late pregnancy, antibody, secretory immunoglobulin A (sIgA), distress, allergy risk, gut immunity, microbi | Edmonton |
2019 |
Even infants at low risk of peanut allergy should eat peanut early |
Elinor Simons | Journal of Allergy and Clinical Immunology: In Practice, peanut allergy, early introduction, food allergy, timing, low-risk, delayed introduction of potentially allergenic foods | Winnipeg |
2019 | Meghan Azad, Kozeta Miliku, Catherine Field | American Journal of Clinical Nutrition, breastmilk, nutrients, longchain polyunsaturated fatty acids, breast milk fats, mothers, diet, fish, omega-3, omega-6, body mass index (BMI), pregnancy, DHA (docosahexaenoic acid), infant brain development | Winnipeg | |
2019 |
Screen time associated with behavioural problems in preschoolers |
Piush Mandhane, Sukhpreet Tamana | PLOS One, University of Alberta, screen time, screen-time, behavioural problems, inattention, attention deficit hyperactivity disorder (ADHD), guidelines, Child Behavior Checklist (CBCL), sleep, organized sports, physical activity, | Edmonton |
2019 | Meghan Azad, Shirin Moossavi | breastmilk, microbiome, microbiota, bacteria, gut, mouth, breastfeeding, direct, indirect, pumped, oral, formula | Winnipeg | |
2019 |
Air pollution exposure in early pregnancy linked to infants’ risk of developing allergies |
Stuart Turvey, Hind Sbihi, Michael Kobor | Journal of Allergy and Clinical Immunology, mother, exposure to traffic-related air pollution (TRAP), pregnancy, allergic sensitization, in utero, asthma, allergies, skin prick test, food allergy, inhaled allergens, Epigenetic gestational age (eGA), ges | Hamilton |
2019 | Piush Mandhane, Anita Kozyrskyj, Brittany Matenchuk | Sleep Medicine, University of Alberta, level of education, prenatal depression, method of delivery, infant sleep duration, maternal distress, emergency cesarean section, vaginal delivery, birth mode | Edmonton | |
2018 |
“Every feed counts”: Breastfeeding may protect against obesity in early life |
Meghan Azad | breastfeeding, obesity, exclusive, dose dependent, Pediatrics, infant weight gain, cardiovascular health, expressed, bottle, pumped, formula, direct, indirect, freezing, thawing, heating, overweight | Winnipeg |
2018 | Anita Kozyrskyj, Mon Tun | University of Alberta, CIHR, Canadian Medical Association Journal (CMAJ), SyMBIOTA, household disinfectants, cleaners, obesity, risk, Lachnospiraceae, infant gut microbiome, body mass index (BMI), overweight, detergents, eco-friendly, multi-surface, aeros | Edmonton | |
2018 | Padmaja Subbarao, Christoffer Dharma | mothers, black, first nations, ethnic minorities, maternal depression, stress, pregnant, psychosocial distress, Canadian Journal of Psychiatry, ethnicity, depressive symptoms | Hamilton | |
2018 |
Lung Clearance Index a sensitive marker for infants at risk for asthma |
Padmaja Subbarao, Zihang Lu | Lung Clearance Index (LCI), asthma, risk, airway disease, airways, Thorax, recurrent wheezing, wheeze, Multiple Breath Washout (MBW), lung function in infants, lung disease | Hamilton |
2018 |
Infants who sleep less may have lower cognitive and language skills by age two |
Piush Mandhane, Lisa Smithson | sleep disruption, cognitive, language skills, snore, sleep-disordered breathing (SDB), apnea, nighttime, nose and ear infections, hearing, speech, viral infections, daycare attendance, skin-prick test, allergic sensitization, acid reflux, smoke, dogs, div | Edmonton |
2018 | Meghan Azad, Kozeta Miliku, Lars Bode | breastmilk, sugars, food allergies, Allergy, sensitization, human milk oligosaccharides (HMOs), skin prick tests, infant gut microbiome, bacteria, bioactive components | Winnipeg | |
2018 |
Infant feeding practices influence a baby’s gut bacteria and risk of becoming overweight |
Meghan Azad, Anita Kozyrskyj, James Scott, Jessica Forbes | infant feeding, gut bacteria, gut microbiome, overweight, exclusive breastfeeding, partial, formula, JAMA Pediatrics, Lachnospiracae, DNA sequences, SyMBIOTA, complementary foods, hospital stay | Winnipeg |
2018 |
Exclusive breastfeeding in hospital associated with longer breastfeeding duration |
Meghan Azad, Lorena Vehling, Maria Mackay, Marusia Kachkowski | exclusive breastfeeding in hospital, duration, formula supplementation, education level | Winnipeg |
2018 |
C-sections and gut bacteria increase risk of childhood obesity |
Anita Kozyrskyj, James Scott, David Guttman, Hein Min Tun | C-section, gut bacteria, childhood obesity, overweight, vaginal birth, cesarean section, gut microbiome, JAMA Pediatrics, stool, sequential mediation, Lachnospiracae | Edmonton |
2018 |
CHILD Study researchers awarded $9.1M toward search for asthma clues in dirty diapers |
Stuart Turvey, Padmaja Subbarao, Michael Kobor, B. Brett Finlay, Allan Becker, Meghan Azad, Fiona Brinkman, Timothy Caulfield,Piush Mandhane,Sara Mostafavi, Anna Goldenberg, Theo Moraes, Wendy Lou, Malcolm Sears | Genome Canada, award, childhood asthma, gut microbiome, genomic, stool, microbes | Hamilton |
2017 |
Study finds delayed food introduction increases risk of sensitization |
Malcolm Sears, Maxwell Tran | Pediatric Allergy and Immunology, potentially allergenic foods, timing, delay, early introduction, cow’s milk products, egg, peanut, sensitization, wheeze, asthma, eczema, allergic rhinitis, CIHR | Hamilton |
2017 | Meghan Azad | European Respiratory Journal, wheezing, wheeze, exclusive breastfeeding, breastmilk, asthma, complementary foods, formula, smoking, education | Winnipeg | |
2017 |
Pet exposure during early life affects infant gut microbiota |
Anita Kozyrskyj, James Scott, David Guttman, Hein Min Tun | furry pets, infant gut microbiota, microbiome, allergic disease, asthma, childhood obesity, bacteria, Group B Streptococcus, DNA sequencing, stool, Microbiome, Nature Outlook | Edmonton |
2017 | Anita Kozyrskyj | University of Alberta, asthma, microbes, gut microbiome, Caucasian, boys, Lactobacillus, sex, girls, Bacteroidaceae, puberty, gender switch, European Respiratory Journal | Edmonton | |
2017 |
Study finds asthma and food allergies predictable at age one |
Malcolm Sears, Maxwell Tran, Judah Denburg | asthma, food allergies, eczema, atopic dermatitis (AD), The Journal of Allergy and Clinical Immunology, atopic march, allergic sensitization, allergic rhinitis, early introduction, food allergy | Hamilton |
2017 | Anita Kozyrskyj, Liane Kang | Brain, Behavior and Immunity, maternal distress, pregnancy, immune system, pre- and postnatal depression, antibody, stress-microbiome-immunity pathway, allergic disease, gut microbiome, allergies, secretory immunoglobulin A (sIgA), breastmilk, exclusive b | Edmonton | |
2017 | Meghan Azad, Annika Klopp | asthma risk, direct breastfeeding, formula, expressed breastmilk, The Journal of Pediatrics, freezing, thawing, heating, pumping, suckling, lungs | Winnipeg | |
2017 | Meghan Azad, Deborah Chan | breastmilk hormones, obesity, human milk, International Journal of Obesity, adiponectin, leptin, insulin, weight-for-length (WFL), body mass index (BMI), ethnicity, age, breastfeeding exclusivity, overweight | Winnipeg | |
2017 |
CHILD Study researchers uncover immune status “shift” during healthy pregnancy |
Kent HayGlass | immune status shift, healthy pregnancy, anti-inflammatory | Winnipeg |
2017 |
CHILD Study data to support new research into child lung health |
Teresa To, Padmaja Subbarao, Wendy Lou | The Hospital for Sick Children (SickKids), award, lung disease, CIHR, air quality, asthma | Toronto |
2017 |
CHILD Study team to study how prenatal artificial sweetener intake affects infant weight |
Meghan Azad, Marie-Claire Arrieta | University of Manitoba, University of Calgary, CIHR, artificial sweeteners, pregnancy, infant weight gain, overweight, microbiome, metabolism, obesity, air quality, lung health, maternal diet | Winnipeg |
2016 | Piush Mandhane, Francois Bolduc | University of Alberta, EBioMedicine, prenatal fruit consumption, developmental testing, cognitive development, maternal diet, pregnancy, IQ scale, fruit flies, brain function | Edmonton | |
2016 |
Consumption of artificially sweetened beverages in pregnancy influences infant BMI |
Meghan Azad | JAMA Pediatrics, body mass index (BMI), artificial sweeteners, in utero, maternal diet, pregnancy, overweight, obesity | Winnipeg |
2016 |
CHILD Study researchers to study environment’s impact on chronic diseases |
Malcolm Sears | award, CIHR, lung health, respiratory diseases, asthma, obesity, cardiometabolic disease | Hamilton |
2015 | Anita Kozyrskyj, James Scott, David Guttman, Meghan Azad | antibiotics, birth, infant gut microbiota, microbiome, labour, delivery, breastfeeding, Bacteroidaceae, Clostridiales, CIHR | Edmonton | |
2015 |
Four gut bacteria decrease asthma risk in first 100 days of life |
Brett Finlay, Stuart Turvey | gut bacteria, asthma risk, microbiome, microbiota, Science Translational Medicine, FLVR, Faecalibacterium, Lachnospira, Veillonella, Rothia, CIHR, hygiene hypothesis, mice | Vancouver |
2015 |
Asthma Society of Canada announces “Clearing the Air” award for leadership in health research |
Malcolm Sears | award, asthma research, leadership, prize | Hamiton |
2015 |
Environmental-exposures study tracks more than 3,200 Canadian babies |
Tim Takaro, Malcolm Sears | indoor and outdoor environmental exposures, Journal of Exposure Science and Environmental Epidemiology, homes, dust, mould, furry pets, chemicals, cleaning products, cooking emissions, second-hand smoke, traffic-related air pollution | Vancouver |
2015 |
Exposure to air pollution in the first year of life increases risk for allergies |
Michael Brauer, Hind Sbihi | Environmental Health Perspectives, outdoor air pollution, allergies, traffic-related air pollution, allergic sensitization, furry pets, attached garage, daycare, siblings | Vancouver |
2015 |
Infant gut bacteria and food sensitization: associations in the first year of life |
Anita Kozyrskyj, James Scott, David Guttman, Meghan Azad | infant b=gut bacteria, microbiome, microbiota, food sensitization, allergy, asthma, Clinical & Experimental Allergy, Enterobacteriaceae, Bacteroidaceae, skin prick test | Edmonton |
2013 | Meghan Azad, Anita Kozyrskyj | infant gut bacteria, microbiome, microbiota, mode of delivery, birth, vaginal, cesarean section, exclusive, partial, breastfeeding, formula, asthma, allergies, cancer, type II diabetes, infant diet | Edmonton |